Breast Cancer : Would you elaborate on using Halaven (Eribulin) as a treatment for metastatic breast cancer? When it can be used, how it works, and its benefit.

Would you elaborate on using Halaven (Eribulin) as a treatment for metastatic breast cancer? When it can be used, how it works, and its benefit.

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Topic Tags:

Metastatic Breast Cancer Medications, Breast Cancer Treatments, Eribulin (Halaven) Mechanism Of Action, Breast Cancer, Breast Cancer Drug Efficacy, Metastatic Breast Cancer, Eribulin (Halaven) Drug Efficacy, Medications, Breast Cancer Medications, Eribulin (Halaven), Secondary Breast Cancer Treatments, Metastatic Breast Cancer Treatments

Diseases:

Breast Cancer

Diseases:

Breast Cancer

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Expert Answers

PaulaRyanMDPhD (Physician - Oncology - Hematology/Oncology (Verified) ) - 05 / 17 / 2012

Eribulin is a newer drug (FDA approved for metastatic breast cancer in 2010) that is effective in individuals who have been previously treated with chemotherapy. In a study, known as the EMBRACE trial, women were assigned to receive eribulin or to the treatment chosen by their doctors as predicted to have the best effect. There was a significant survival benefit of about 2.5 months in favor of the eribulin. The drug, derived from sea sponges, works by targeting a scaffolding protein (microtubule) within a cell and interferes with the construction of the scaffolding and stops the cancer cell from dividing.

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