What treatments are available for hyperpigmentation of the hands and feet?

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JKJones (Pharmacist (Verified) ) - 11 / 08 / 2010

Many chemotherapy treatments will have a side effect of hyperpigmentation of the hands and feet. Hyperpigmentation is temporary and will eventually resolve once the drug causing the change is stopped.

If there is itching oral antihistamines such as diphenhydramine may help.

Over the counter creams to lighten the skin may include:
- hydroquinone
- kojic acid
- alpha hydroxy acids
- azelaic acid
- ascorbic acid
- tretinoin (Retinol)
- licorice extract
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