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What tests and metrics are followed during treatment of mantle cell lymphoma?
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JiaRuanMDPhD (Physician - Oncology - Hematology/Oncology (Verified) ) - 08 / 04 / 2012
During treatment, the medical oncologists and their teams work very closely with the patients to monitor [1] response to therapy, and [2] potential treatment-related toxicities. Response assessment would follow all aspects of disease involvement, and typically include physical exam to see if palpable lymph node or spleen enlargement has decreased, blood tests to evaluate whether blood counts have improved, and periodic CT or PET scan to measure changes in lymph node / spleen sizes. For patients who have resolved all measurable disease on the scans, their oncologists may propose to repeat a bone marrow biopsy (if the bone marrow was initially involved by disease) in order to document complete response. In the meantime, evaluation of side effects is equally important to determine if the treatment is safe for a particular patient, and whether modification of medication dosage or treatment schedule is warranted.
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