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What process do you follow to determine the recommended radiation therapy treatment for brain cancer?
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MineshMehtaMD (Physician - Oncology - Radiation (Verified) ) - 07 / 05 / 2012
The process for selecting the appropriate radiotherapeutic treatment for a patient takes into account several variables. The first question that needs to be addressed is whether after a comprehensive assessment of the diagnosis, imaging, and the patient’s overall status, including physiologic and metastatic assessement, whether radiation therapy is indicated in either a palliative, curative, ablative, adjuvant, or co-operative (with chemotherapy, etc.) context. If the answer to this first question is yes, the next determination is whether radiotherapy would be used as a sole modality, or in combination with other therapies, and if the latter approach is selected, the exact timing and sequencing become important. This takes into account the potential for synergistic benefit as well as the possibility of additive toxicities. If radiotherapy is to be used either singly or in combination, the next question is appropriate dose and fractionation selection, such as a single fraction, 5 fractions, a 2-week schedule, or a much longer schedule, for example.
The next step in the decision making processing is the actual target selection, and the treatment technical parameters necessary to achieve an appropriate conformal dose to the selected target whilst minimizing the dose to surrounding normal tissue. This would require an assessment of one or more technical approaches to delivering radiotherapy, such as 2D, 3D, IMRT, IGRT, etc. Therefore, the decision-making can be quite complex.
The next step in the decision making processing is the actual target selection, and the treatment technical parameters necessary to achieve an appropriate conformal dose to the selected target whilst minimizing the dose to surrounding normal tissue. This would require an assessment of one or more technical approaches to delivering radiotherapy, such as 2D, 3D, IMRT, IGRT, etc. Therefore, the decision-making can be quite complex.
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