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What is the role of radiation therapy for treating cervical cancer?
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MarneeSpiererMD (Physician - Oncology - Radiation (Verified) ) - 04 / 02 / 2012
Primary treatment is determined by the FIGO (International Federation of Gynecology and Obstetrics) stage. Primary surgical management with hysterectomy is typically indicated in early stage cancers (IA1–IIA), as these cancers are considered resectable. However, primary radiation may also be considered. We have data that show equivalent tumor control and survival between surgery and radiation in early stage disease. For those patients who undergo surgery, some may need post-operative radiation therapy or post-operative concurrent chemotherapy and radiation. We have data that show a decreased rate of local recurrence +/- an improvement in survival with the addition of adjuvant treatment (either radiation alone or radiation + chemotherapy after surgery). The decision to use radiation alone as an adjuvant treatment or radiation with chemotherapy depends on the pathologic findings at the time of surgery. Locally advanced cases (unresectable) - some IB2 and stages IIB-IVA - are treated with a combination of radiation with concurrent chemotherapy. We have data that show superior outcomes with radiation and concurrent chemotherapy versus radiation alone.
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