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What is the role of genetics in treating gastric (stomach) cancer?
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ZevWainbergMD (Physician - Oncology - Hematology/Oncology (Verified) ) - 06 / 25 / 2012
There are some hereditary conditions that can predispose a person to developing gastric cancer. Some cases of Lynch syndrome (which more commonly causes colon cancer) can also cause gastric cancer. A rarer disorder is an inherited mutation in a gene called E-Cadherin which can lead to Hereditary Diffuse Gastric Cancer, this is extremely rare and is usually seen in families who have multiple members who have gastric cancer. If one has a strong family history of this disease, it should be discussed with the oncologist and one could consider genetics counselling.
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