What is the difference between neulasta and neupogen?

Expert Answers

JKJones (Pharmacist (Verified) ) - 11 / 09 / 2010

Neulasta and neupogen are similar molecules.

The primary difference is that Neulasta has a PEG (polyehtylene glycol) incorporated in its composition, thereby lengthening its duration of action. As a result, Neulasta is administered on a less frequent schedule. It is typically injected once for each cycle of high-dose chemotherapy 24 hours after chemo and no sooner than 14 days before your next chemo treatment.

Neupogen is typically injected on a daily basis until your neutrophil counts come back to normal levels. Neupogen may work fine with just weekly chemo treatments or it may be given as often as you need between chemo cycles.
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