What is the current status of breast cancer vaccine research and what are the next steps in research?
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Expert AnswersDrKathleenTRuddy (Physician - Surgery - Breast (Verified) ) - 08 / 02 / 2011
Therapeutic vaccines targeting specific proteins are being tested, some with promising results. The first preventive breast cancer vaccine was developed by Professor Vincent Tuohy of the Cleveland Clinic and published last year in Nature Medicine (May 2010). The vaccine is 100% effective in preventing breast cancer in mice and also capable of slowing the growth of tumors that have already formed. It was also effective against a cell line of triple-negative breast cancer. Tuohy's vaccine is ready to Phase I studies in women, provided he receives the funding necessary to get the clinical trials funded: approximately 5 million to start and, likely, 20 million to fund through Phase III studies.
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