Melanoma (Cutaneous) : What follow up do you recommend for uveal melanoma patients who complete treatment and are NED?

What follow up do you recommend for uveal melanoma patients who complete treatment and are NED?

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Melanoma (Cutaneous)

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Melanoma (Cutaneous)

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Expert Answers

ScottWoodmanMDPhD (Physician - Oncology - Hematology/Oncology (Verified) ) - 08 / 19 / 2012

There is not a universal standard for how patients that have no evidence of disease (NED) following treatment of their primary uveal melanoma should be followed. Typically, imaging is performed every 6 months to identify metastatic disease (uveal melanoma arising outside the eye). Either CT scans (preferably using a protocol that optimizes the contrast in the liver) or MRI scans are used. Abdominal ultrasound is also used, but does not always provide the best visualization of potential tumors within the liver. In addition to imaging studies, physicians tend to order some blood tests that measure liver function. There is an effort in the uveal melanoma clinical research community to adopt more universal standards, however studies to support clear recommendations are lacking. It is also the case that the genetics that underlie one’s uveal melanoma tumor may influence the type and time interval of follow-up screening (i.e., high risk vs. low risk of metastasis).

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