What factors determine the aggressiveness of a prostate cancer?

Topic Tags:  
Topic Tags:  
Diseases:  
Diseases:  
Emailz
1
Expert Answers

SandySrinivasMD (Physician - Oncology - Hematology/Oncology (Verified) ) - 12 / 03 / 2012

Typically when a patient is diagnosed with prostate cancer, several things are looked at. They include serum PSA, Gleason’s grade, and findings on a digital exam. Based on these 3 factors patients are classified as low, intermediate and high risk of having disease outside the prostate. Additional features include number of positive biopsies, number of biopsies with a high Gleason’s grade, % of tumor involved in each biopsy core. The rate of change of PSA within the last year is also helpful in determining aggressiveness. Having a Gleason’s grade of 4 or 5, or a PSA >20 or an abnormal rectal exam may determine that a patient has high-risk disease. These patients will get additional scans to ensure that the disease has not spread outside the prostate. Typically this group gets aggressive therapy with more than 1 mode of treatment such as surgery with or without radiation, or radiation with hormonal therapy.

Active research is ongoing evaluating biomarkers in blood and urine to determine if aggressiveness can be better determined when one is diagnosed with prostate cancer.
Join Now to ask a follow-up question or share your experience!
We'll help guide and support you through treatments.
Similar Questions
What factors are important in determining the prognosis for a castrate resistant prostate cancer patient?
What is PCA3 and how is it used to help determine risk of prostate cancer?
What process does the pathologist follow to determine the Gleason score of a prostate cancer?
What measurements determine if a prostate cancer patient is at moderate risk?
How does the pathologist determine the type of prostate cancer?
Note: All content on this site is informational and not a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider with questions regarding your health.
Note: Usernames have been made anonymous and profile images are not shown to protect the privacy of our members.
Flag Content
Please explain why you are flagging this content. Thank you.
Thank you for flagging this content. We will look into it right away.
Give a 'Thank you' to
Close
Talk About Health
Add Answer

Close
1) Question:
2) Background Info (optional): What context or background information is relevant to this request?
Notes:
The more clear and thorough your request, the more likely you will receive support.
Many of our members are learning from this information or english might not be their first language. Please use standard english and spell out all words. For example, use 'you' instead of 'u'.
Close
Talk About Health
Please join TalkAboutHealth and you will be able to ask questions.
Newsletters
Close
Subscribe to our free updates for the latest news, best answers and featured experts!
Your Email:
Q&A Workshop Announcements
(Featured experts, answers, tips, & latest news.)
Q&A Workshop Summaries
(Answer summaries from our expert Q&A workshops.)
Best of TalkAboutHealth (weekly)
(The week's best answers, news & support.)
TalkAboutHealth Benefits
(Custom health, wellness & medical promotions from our partners.)

Partners become a partner

© Copyright 2014 - Talk About Health - Privacy Policy | Terms of Service
x Don't show again
Like us on Facebook?