What factors determine how aggressive a non-Hodgkin lymphoma is?

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MichaelGrossbardMD (Physician - Oncology - Hematology/Oncology (Verified) ) - 07 / 05 / 2012

Multiple factors determine the aggressiveness of a non-Hodgkin’s lymphoma. The specific subtype of lymphoma is the simplest way in which to assess a lymphoma’s aggressiveness. In the simplest sense, lymphomas can be divided into indolent lymphomas and aggressive lymphomas. Indolent lymphomas grow very slowly, often over months to years, and may not require any treatment for several years after diagnosis. In contrast, aggressive lymphomas can grow very rapidly. Burkitt’s lymphoma is a particularly aggressive non-Hodgkin’s lymphoma and the tumor cells can divide every 24 hours. The most aggressive lymphomas need to be treated shortly after diagnosis and require treatment with multiple chemotherapy agents given on a specified schedule.
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