What are tumorgrafts and how can they help me personalize my cancer treatment?

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DavidSidranskyMD (Physician - Oncology - Hematology/Oncology (Verified) ) - 08 / 28 / 2012

Every patient’s cancer is unique. Two patients with the same type of cancer will often respond differently to the same treatment. Tumorgrafts are pieces of living tumor tissue from a specific patient that are implanted (or grafted) into a mouse. Once the patients tumor (graft) begins to grow in the mice, it can be expanded in additional mice and tested against different cancer drugs. The graft can be used to personalize cancer therapy by finding the drug or combination of drugs that works best to shrink the tumor in the mouse. This information can then be used by the treating physician to personalize the patient’s cancer care.
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