What are the differences between the BRCA1+ and BRCA2+ mutations?

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StevenNarodMD (Physician (Verified) ) - 08 / 13 / 2012

BRCA1 and BRCA2 genes are two genes but are related in the same pathway. In practical terms, the risk of ovarian cancer is less for women with a BRCA2 mutation (about 20%) than for women with a BRCA1 mutation (about 40%). The risks for breast cancer are about the same (70% lifetime).
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