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What are the components of the tumor microenvironment that enable tumor growth?
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StevenLibuttiMD (Physician (Verified) ) - 08 / 05 / 2012
There are several components of the tumor microenvironment that can influence tumor growth. Among them are endothelial cells or blood vessels, fibroblasts, macrophages and elements of the structural matrix such as collagen and fibronectin. Tumor cells can secrete factors that influence these components and the components themselves can produce factors that influence the tumor. Oxygen and the pH of the surrounding tissues also play a role.
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