Translational Research

I am guessing that you are asking how you develop a novel biomarkers or a new targeted therapy for breast cancer or inflammatory breast cancer.


There are several ways to approach this issues.

1. You collect large amoung of tissue and blood samples from breast cancer. Then you do a comprehensive analysis of genetic and protein changes (DNA, RNA, and protein). You link this data to a clinica data and find the one or them that can impact surveil or disease recurrence.

2. The other approach is discovery from basic research needs to be mined. And take their knowledge to apply by conducting a hypothesis oriented research. This means that you build up the puzzle one by one to prove the target is truly relevant in breast cancer.

Both approaches are important. Therefore, we do both and spend tremendous amount of time an money to come out with a strong scientific rationale before we can test this in human being. The problem we face is that there is not enough money and those who qualified to do this type of research.

Please asks me a more specific question. This may help me to answer this more accurately. I am guessing that you are asking how you develop a novel biomarkers or a new targeted therapy for breast cancer or inflammatory breast cancer.


There are several ways to approach this issues.

1. You collect large amoung of tissue and blood samples from breast cancer. Then you do a comprehensive analysis of genetic and protein changes (DNA, RNA, and protein). You link this data to a clinica data and find the one or them that can impact surveil or disease recurrence.

2. The other approach is discovery from basic research needs to be mined. And take their knowledge to apply by conducting a hypothesis oriented research. This means that you build up the puzzle one by one to prove the target is truly relevant in breast cancer.

Both approaches are important. Therefore, we do both and spend tremendous amount of time an money to come out with a strong scientific rationale before we can test this in human being. The problem we face is that there is not enough money and those who qualified to do this type of research.

Please asks me a more specific question. This may help me to answer this more accurately.