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Solvent Polyoxyethylated Castor Oil
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- Higher doses of paclitaxel can be delivered without the need for solvents.
- A higher percentage of the paclitaxel reaches the tumor because albumin receptors in breast cancer cells prefer albumin as their delivery packet because albumin normally transports nutrients to cells.
Additionally, Abraxane
- has decreased side effects due to solvent related (polyoxyethylated castor oil found in Taxol) hypersensitivity reactions.
- decreased use of medications to help prevent the solvent (polyoxyethylated castor oil) hypersensitivity reactions.
- The intravenous time of administration is decreased.
Here are a couple of more resources on abraxane:
http://www.medscape.com/viewarticle/465645
http://www.webmd.com/breast-cancer/features/new-treatments-for-breast-cancer?page=1%20&%202
It is believed that Abraxane is more effective at treating tumors than Taxol for the following reasons:
- Higher doses of paclitaxel can be delivered without the need for solvents.
- A higher percentage of the paclitaxel reaches the tumor because albumin receptors in breast cancer cells prefer albumin as their delivery packet because albumin normally transports nutrients to cells.
Additionally, Abraxane
- has decreased side effects due to solvent related (polyoxyethylated castor oil found in Taxol) hypersensitivity reactions.
- decreased use of medications to help prevent the solvent (polyoxyethylated castor oil) hypersensitivity reactions.
- The intravenous time of administration is decreased.
Here are a couple of more resources on abraxane:
http://www.medscape.com/viewarticle/465645
http://www.webmd.com/breast-cancer/features/new-treatments-for-breast-cancer?page=1%20&%202
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