Paclitaxel

Paclitaxel is a chemotherapeutic agent (chemotherapy drug) used to treat breast cancer. It belongs to a group of anti-cancer medications called taxanes.

Paclitaxel works by inhibiting or stopping cancer cell division. Drugs that inhibit cell division are called mitotic inhibitors. Paclitaxel was found and isolated from the bark of the Pacific Yew tree. It is now produced using plant cell fermentation technology.

It is surmised that cells treated with Paclitaxel have defects in mitotic spindle assembly (framework of cells), chromosome segregation, and cell division.

Paclitaxel is a chemotherapeutic agent (chemotherapy drug) used to treat breast cancer. It belongs to a group of anti-cancer medications called taxanes.

Paclitaxel works by inhibiting or stopping cancer cell division. Drugs that inhibit cell division are called mitotic inhibitors. Paclitaxel was found and isolated from the bark of the Pacific Yew tree. It is now produced using plant cell fermentation technology.

It is surmised that cells treated with Paclitaxel have defects in mitotic spindle assembly (framework of cells), chromosome segregation, and cell division.

It is believed that Abraxane is more effective at treating tumors than Taxol for the following reasons:
- Higher doses of paclitaxel can be delivered without the need for solvents.
- A higher percentage of the paclitaxel reaches the tumor because albumin receptors in breast cancer cells prefer albumin as their delivery packet because albumin normally transports nutrients to cells.

Additionally, Abraxane
- has decreased side effects due to solvent related (polyoxyethylated castor oil found in Taxol) hypersensitivity reactions.
- decreased use of medications to help prevent the solvent (polyoxyethylated castor oil) hypersensitivity reactions.
- The intravenous time of administration is decreased.

Here are a couple of more resources on abraxane:
http://www.medscape.com/viewarticle/465645
http://www.webmd.com/breast-cancer/features/new-treatments-for-breast-cancer?page=1%20&%202
It is believed that Abraxane is more effective at treating tumors than Taxol for the following reasons:
- Higher doses of paclitaxel can be delivered without the need for solvents.
- A higher percentage of the paclitaxel reaches the tumor because albumin receptors in breast cancer cells prefer albumin as their delivery packet because albumin normally transports nutrients to cells.

Additionally, Abraxane
- has decreased side effects due to solvent related (polyoxyethylated castor oil found in Taxol) hypersensitivity reactions.
- decreased use of medications to help prevent the solvent (polyoxyethylated castor oil) hypersensitivity reactions.
- The intravenous time of administration is decreased.

Here are a couple of more resources on abraxane:
http://www.medscape.com/viewarticle/465645
http://www.webmd.com/breast-cancer/features/new-treatments-for-breast-cancer?page=1%20&%202

Benefits of Abraxane vs. Taxol or Onxal are:
- more effective at treating tumors because a higher dosage can be delivered.
- decrease in side effects from solvent related hypersensitivity reactions.
- decreased use of medications to combat the solvent related hypersensitivity reactions.
- decreased time of administration.

The disadvantage is that the Abraxane is more expensive than the Taxol or Onxal.

Here are a couple of more resources on abraxane:
http://www.medscape.com/viewarticle/465645
http://www.webmd.com/breast-cancer/features/new-treatments-for-breast-cancer?page=1%20&%202 Benefits of Abraxane vs. Taxol or Onxal are:
- more effective at treating tumors because a higher dosage can be delivered.
- decrease in side effects from solvent related hypersensitivity reactions.
- decreased use of medications to combat the solvent related hypersensitivity reactions.
- decreased time of administration.

The disadvantage is that the Abraxane is more expensive than the Taxol or Onxal.

Here are a couple of more resources on abraxane:
http://www.medscape.com/viewarticle/465645
http://www.webmd.com/breast-cancer/features/new-treatments-for-breast-cancer?page=1%20&%202

Paclitaxel is the active drug in Taxol and Abraxane. The difference between Taxol and Abraxane is that they use different formulations to deliver paclitaxel to the body. Specifically, Taxol contains paclitaxel dissolved in polyoxyethylated castor oil. In contrast, in Abraxane, paclitaxel is encapsulated in albumin, a human protein.

Here are a couple of more resources on abraxane:
http://www.medscape.com/viewarticle/465645
http://www.webmd.com/breast-cancer/features/new-treatments-for-breast-cancer?page=1%20&%202 Paclitaxel is the active drug in Taxol and Abraxane. The difference between Taxol and Abraxane is that they use different formulations to deliver paclitaxel to the body. Specifically, Taxol contains paclitaxel dissolved in polyoxyethylated castor oil. In contrast, in Abraxane, paclitaxel is encapsulated in albumin, a human protein.

Here are a couple of more resources on abraxane:
http://www.medscape.com/viewarticle/465645
http://www.webmd.com/breast-cancer/features/new-treatments-for-breast-cancer?page=1%20&%202

Pain may be a side effect of Paclitaxel. If pain is caused from Paclitaxel, it is usually temporary (2-3 days).

To alleviate the pain, you may take over the counter pain medications such as anti-inflammatory agents (ibuprofen). If the pain is more severe, you physician may prescribe pain medications. Pain may be a side effect of Paclitaxel. If pain is caused from Paclitaxel, it is usually temporary (2-3 days).

To alleviate the pain, you may take over the counter pain medications such as anti-inflammatory agents (ibuprofen). If the pain is more severe, you physician may prescribe pain medications.