In what situations is a bone marrow transplant considered to treat mantle cell lymphoma?

Topic Tags:  
Topic Tags:  
Done
Diseases:  
Diseases:  
Done
Emailz
1
Expert Answers

JiaRuanMDPhD (Physician - Oncology - Hematology/Oncology (Verified) ) - 08 / 04 / 2012

Both autologous (from self) and allogeneic (from others) stem cell transplant (SCT) have been used in mantle cell lymphoma. Autologous transplant is often considered as a consolidation measure for patients younger than 65 years of age who have achieved a good response with frontline chemotherapy-based regimen. Data from European MCL registry and studies in US have shown that autologous SCT can maintain an additional 2-3 years of remission following frontline treatment such as R-CHOP. A majority of patients, however, will eventually relapse from their disease following autologous SCT. Allogeneic SCT are generally considered for patients with HLA-matched donors who have relapsed diseases. Given the significant treatment-related toxic side effects associated with bone marrow transplant, consultation with an established bone marrow transplant group with a clinical focus on lymphoma should be encouraged.
Join Now to ask a follow-up question or share your experience!
We'll help guide and support you through treatments.
Similar Questions
In what situations is a stem cell transplant used to treat chronic myeloid leukemia (CML)?
If a bone marrow transplant is not accepted by the patient, what happens next?
What is an umbilical cord bone marrow transplant and who is eligible for this procedure?
When mantle cell lymphoma progresses after the first line of treatments, what are the next steps?
How is mantle cell lymphoma different from other lymphomas?
Note: All content on this site is informational and not a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider with questions regarding your health.
Note: Usernames have been made anonymous and profile images are not shown to protect the privacy of our members.
Flag Content
Please explain why you are flagging this content. Thank you.
Cancel
Thank you for flagging this content. We will look into it right away.
Ok
Give a 'Thank you' to
Cancel
Close
Talk About Health
Add Answer

Close
1) Question:
2) Background Info (optional): What context or background information is relevant to this request?
Notes:
The more clear and thorough your request, the more likely you will receive support.
Many of our members are learning from this information or english might not be their first language. Please use standard english and spell out all words. For example, use 'you' instead of 'u'.
Newsletters
Close
Subscribe to our free updates for the latest news, best answers and featured experts!
Your Email:
Q&A Workshop Announcements
(Featured experts, answers, tips, & latest news.)
Q&A Workshop Summaries
(Answer summaries from our expert Q&A workshops.)
Best of TalkAboutHealth (weekly)
(The week's best answers, news & support.)
TalkAboutHealth Benefits
(Custom health, wellness & medical promotions from our partners including clinical trials, market research opportunities, & new programs.)

Partners become a partner

© Copyright 2013 - Talk About Health - Privacy Policy | Terms of Service