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How can I get accurate risk information for my 26 year old daughter? We have 4 diagnoses of 1st and 2nd degree relatives, 3 premenopausal. No known BRCA.

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Cancer Risk Breast Cancer High Risk Breast Cancer Risk

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Cancer Risk X Breast Cancer High Risk X Breast Cancer Risk X

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Diseases:

Breast Cancer

Diseases:

Breast Cancer

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Answers (2)

Tobey (Support Group (Verified) ) - 01 / 26 / 2012

Hi AnneMarie,
I would suggest that you call your genetic counselor. The genetic counselor knows your history & can advise you best..That's just MY OPINION!
xoxo Tobey

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MelanieBoneMD (Physician - OBGYN - Obstetrics-Gynecology (Verified) ) - 01 / 26 / 2012

Hard question to answer. In addition to BRCA, did anybody undergo BART testing? This test is for large DNA rearrangements and is done through Myriad Genetics. If it has been done, then your family falls in a high-risk familial breast cancer category. I would treat y daughter's breasts as if there were a BRCA mutation in the family and offer annual MRI alternating with mammogram and sonogram every 6 months. In between I would suggest that she have clinical breast exams, one by her gynecologist and one by a breast surgeon. If she is exceedingly anxious or is hard to examine, I would consider prophylactic mastectomies with immediate reconstruction. It cannot totally eliminate the risk of cancer, but brings it down to less than that of the general public. The reason risk still exists is that a minute amount of breast tissue remains after a mastectomy and could still result in a breast cancer, but there is nothing better available at this time.

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Latest Activity: 01 / 26 / 2012
Views: 224
Followed By: 3 members