Hormone Receptor Negative Breast Cancer

I agree with JKJones. There's no conclusive evidence that tamoxifen works for estrogen-receptor-negative breast cancer. Scientific studies have shown that tamoxifen reduces the occurrence of estrogen-receptor-positive cancers, but there is no difference in the outcomes for estrogen-receptor-negative cancers.

Tamoxifen is not effective against hormone-receptor-negative breast cancer because hormone-receptor-negative breast cancer (as the name states) does not have hormone receptors.

However, there are other studies to take into consideration regarding tamoxifen and hormone-receptor-negative breast cancer, but none are conclusive.

- A study at University of Texas M.D. Anderson Cancer Center that reduced the diagnosis time of estrogen-receptor-negative breast cancers in patients taking tamoxifen.
- A study at Fred Hutchinson Cancer Research Center indicated that tamoxifen may result in increased chance of developing hormone-receptor-negative cancer.

http://www.breastcancer.org/treatment/hormonal/new_research/20081007.jsp
http://www.cancer.gov/cancertopics/factsheet/Therapy/tamoxifen
http://www.news-medical.net/news/20090826/Tamoxifen-drug-poses-increased-risk-of-developing-ER-negative-breast-cancer.aspx