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For stage 2 melanoma, what are the adjuvant therapy treatment options?
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KimMargolinMD (Physician - Oncology - Hematology/Oncology (Verified) ) - 08 / 06 / 2012
There is no proven beneficial systemic therapy for patients with stage II melanoma. Many laboratories and clinical investigators are working on various forms of immunotherapy that may be safe and effective in higher-risk stages and could then be moved into the stage II arena. Immunotherapies will probably be the most important adjuvant therapies, as they are likely to have a favorable therapeutic index, defined as the relative risk (side effects and toxicities) versus benefit (enhancing the time free of relapse and possibly enhancing survival). Among the immunotherapies likely to be effective and safe in Stage 2 melanoma will be vaccines and related treatments that can be given safely to large groups of patients for long periods of time. If effective, some of these strategies may even find a place in prevention of new melanomas in individuals at high risk.
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