Typically it decided based on the results of clinical trials. We test different drugs with a large population of breast cancer patients and then whichever one is the most effective is the one that becomes the standard of care (i.e. the one that we choose first). If there are reasons why that person can’t tolerate that regimen then we may have to alter that plan. There may be sometimes where there are regimens that are equal and then it is based on side effects or logistics (how often the infusion ).
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