Can you explain what MBI (Molecular Breast Imaging) / Breast Specific Gamma Imaging (BSGI) is?

I'm unsure what Molecular Breast Imaging is, exactly. Have a good grasp of what a molecule is, and can't imagine how that works with breast screening. Thanks in advance :-)

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member9978 (other) - 03 / 18 / 2011

1 vote(s) by murray
Molecular Breast Imaging (MBI) is currently not approved as a screening option for breast cancer. Preliminary studies from the Mayo Clinic show promising results to reduce the radiation dose of this procedure to be equivalent of a mammogram so that MBI can be used as a screening tool. MBI (also referred to as Breast Specific Gamma Imaging) is currently approved as a diagnostic tool following screening via mammography and ultrasound. Recent published guidelines detail the use of MBI and can be found at http://interactive.snm.org/docs/BreastScintigraphyGuideline_V1.0.pdf

murray (Family member) - 03 / 12 / 2011

Molecular breast imaging (MBI) is a new screening method for breast cancer that is especially effective in detecting tumors in dense breast tissue that mammograms may miss.

MBI works using a gamma radiation-detecting camera. The patient is injected with short-lived radioactive agent. The tumor cells absorb the radioactive agent. The tumors are able to be seen/detected in the resulting image from the camera.

According to a Mayo Clinic study, "MBI detected three times as many cancers in women with dense breast tissue and an increased risk of breast cancer." MBI also had fewer false positives according to the study. - http://www.mayoclinic.org/news2009-mchi/5203.html

Originally, the radiation dose of this procedure was much more than a mammogram. According to Mayo though, the radiation dose is now the same as a mammogram.
http://discoverysedge.mayo.edu/molecular-breast-imaging/
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