Are certain breast cancer types more likely to be related to having the BRCA 1/2 mutation?

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Although I am the first in our family (as far as I know) to be diagnosed, there may be a need for another family member to know if we carry BRCA mutation. Is there a relationship between tumour pathology/ hormone receptors and HER status etc and likelihood of BRCA gene?

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Topic Tags:

BRCA-1, Breast Cancer, BRCA Mutations, BRCA-2, Breast Cancer Types

Topic Tags:

BRCA-1 X Breast Cancer X BRCA Mutations X BRCA-2 X Breast Cancer Types X

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Expert Answers

RobertQuinlanMD (Physician - Surgery - Surgical Oncology (Verified) ) - 09 / 07 / 2011

BrCa 1 is more often associated with estrogen and progesterone receptor protein NEGATIVE tumors and are also more often her-2-neu negative (triple negative) than tumors seen in sporadic (non hereditary) breast cancer. BrCa 2 tumors are more like sporadic breast cancers in their molecular signatures.

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