Antineoplastic Agent

Letrozole is categorized pharmacologically as an Antineoplastic Agent and as an Aromatase Inhibitor. The action of Aromatase Inhibitors is to inhibit the production of estrogens by stopping the conversion of androgen into estrogen.

- Aromatase Inhibitors operate by blocking the aromatase enzyme from converting androgen to estrogen in women who have gone through menopause.
- Post-menopausal women get estrogen from the conversion of androgen into estrogen in the tissues of the body.
- In contrast women who have not gone through menopause receive their estrogen from the ovaries.
- By inhibiting the production of estrogen, the estrogen receptor [ER]-positive and/or progesterone receptor [PR]-positive tumor breast cancer cells cannot grow. Letrozole is categorized pharmacologically as an Antineoplastic Agent and as an Aromatase Inhibitor. The action of Aromatase Inhibitors is to inhibit the production of estrogens by stopping the conversion of androgen into estrogen.

- Aromatase Inhibitors operate by blocking the aromatase enzyme from converting androgen to estrogen in women who have gone through menopause.
- Post-menopausal women get estrogen from the conversion of androgen into estrogen in the tissues of the body.
- In contrast women who have not gone through menopause receive their estrogen from the ovaries.
- By inhibiting the production of estrogen, the estrogen receptor [ER]-positive and/or progesterone receptor [PR]-positive tumor breast cancer cells cannot grow.

Paclitaxel is a chemotherapeutic agent (chemotherapy drug) used to treat breast cancer. It belongs to a group of anti-cancer medications called taxanes.

Paclitaxel works by inhibiting or stopping cancer cell division. Drugs that inhibit cell division are called mitotic inhibitors. Paclitaxel was found and isolated from the bark of the Pacific Yew tree. It is now produced using plant cell fermentation technology.

It is surmised that cells treated with Paclitaxel have defects in mitotic spindle assembly (framework of cells), chromosome segregation, and cell division.

Paclitaxel is a chemotherapeutic agent (chemotherapy drug) used to treat breast cancer. It belongs to a group of anti-cancer medications called taxanes.

Paclitaxel works by inhibiting or stopping cancer cell division. Drugs that inhibit cell division are called mitotic inhibitors. Paclitaxel was found and isolated from the bark of the Pacific Yew tree. It is now produced using plant cell fermentation technology.

It is surmised that cells treated with Paclitaxel have defects in mitotic spindle assembly (framework of cells), chromosome segregation, and cell division.